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MiloPhene™ (clomiPHENE citrate) Tablets, USP (generic Clomid®).
Product Details.
Clomiphene citrate is indicated for the treatment of ovulatory dysfunction in women desiring pregnancy. Impediments to achieving pregnancy must be excluded or adequately treated before beginning clomiphene citrate therapy. Those patients most likely to achieve success with clomiphene therapy include patients with polycystic ovary syndrome, amenorrhea-galactorrhea syndrome, psychogenic amenorrhea, post-oral-contraceptive amenorrhea, and certain cases of secondary amenorrhea of undetermined etiology.
Treatment of the selected patient should begin with a low dose, 50 mg daily (1 tablet) for 5 days. The dose should be increased only in those patients who do not ovulate in response to cyclic 50 mg clomiphene citrate. Please click here for full Prescribing Information and Patient Information.
What to Expect.
Studies report that between 70% and 80% of women with ovulatory disorders will ovulate successfully with clomiphene citrate treatment, typically within the first three cycles. The pregnancy rate per cycle is approximately 10-12%.
Safety Information.
Careful attention should be given to the selection of candidates for clomiphene citrate therapy. Pelvic examination is necessary prior to clomiphene citrate treatment and before each subsequent course. Click here for contraindications and warnings.
MiloPhene should not be used in patients with:
- Pregnancy: The drug may cause fetal harm and is contraindicated in pregnant women.
- Liver Disease: Patients with liver disease or a history of liver dysfunction should not use this medication.
- Abnormal Uterine Bleeding: It is contraindicated in patients with abnormal vaginal bleeding of undetermined origin.
- Ovarian Cysts: Use is contraindicated in patients with ovarian cysts or enlargement not due to polycystic ovarian syndrome (PCOS). A pelvic exam is necessary before each course of treatment.
- Other Conditions: It should not be used in patients with uncontrolled thyroid or adrenal dysfunction, or in the presence of an organic intracranial lesion such as a pituitary tumor.
- Hypersensitivity: Patients with a known hypersensitivity to clomiphene or any of its ingredients. Please click here for the complete warning and precautions.
Please click here for full Prescribing Information and Patient Information.
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