Estradiol Vaginal Inserts (Generic VAGIFEM®) Single Use Applicator.

Report any unusual vaginal bleeding right away while you are using the estradiol patch. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider should check any unusual vaginal bleeding to find out the cause. Please click here for the complete boxed warning

If you have a uterus, talk to your healthcare provider about whether the addition of a progestogen is right for you. In general, the addition of a progestogen is recommended for women with a uterus to reduce the chance of getting cancer of the uterus (womb). See your healthcare provider right away if you get vaginal bleeding while using the estradiol vaginal insert. Please click here for more Important Risk Information. If you are concerned that you are having side effects related to the medication, please consult your doctor.

Please click here for full Prescribing Information and Patient Information.