Product Details

Estradiol is used to reduce moderate to severe hot flashes and to treat dryness, itching, and burning in or around the vagina, difficulty or burning on urination associated with menopause. If you use estradiol only to treat your dryness, itching, and burning in and around your vagina, talk with your healthcare provider about whether a topical vaginal product would be better for you.

Estradiol is used to treat certain conditions in which a young woman’s ovaries do not produce enough estrogen naturally; to treat certain types of abnormal vaginal bleeding due to hormonal imbalance when your doctor has found no serious cause of the bleeding; to treat certain cancers in special situations in men and women; and to prevent thinning of bones.  If you use estradiol only to prevent osteoporosis from menopause, talk with your healthcare provider about whether a different treatment or medicine without estrogens might be better for you.

You and your healthcare provider should talk regularly about whether you should continue with estradiol.

What to Expect

You may feel some relief from your symptoms within four weeks after starting treatment.

Select Safety Information

Estrogens increase the chances of getting cancer of the uterus. Report any unusual vaginal bleeding right away while you are taking estrogens. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider should check any unusual vaginal bleeding to find out the cause. Please click here for the complete boxed warning.

While you are using estrogens, it is important to visit your doctor at least once a year for a check-up. If you have a uterus, talk to your healthcare provider about whether the addition of aprogestin is right for you. Please click here for more Important Risk Information.

If you are concerned that you are having side effects related to the medication, please consult your doctor.

Please click here for full Prescribing Information and Patient Information.